The a16z Show

The a16z Show

Andreessen Horowitz

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Episode (200)

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21
Andrew Huberman: Peptides, Sleep Tech, and the End of Obesity

Andrew Huberman: Peptides, Sleep Tech, and the End of Obesity

Mar 09, 2026

Daisy Wolf speaks with Dr. Andrew Huberman, professor of neurobiology and ophthalmology at Stanford University and host of the Huberman Lab podcast. They discuss how the pandemic sparked a consumer he...

22
Atlassian CEO on the SaaS Apocalypse, AI Agents & What Comes Next

Atlassian CEO on the SaaS Apocalypse, AI Agents & What Comes Next

Mar 06, 2026

Alex Rampell and Erik Torenberg speak with Mike Cannon-Brookes, cofounder and CEO of Atlassian, about how to make sense of the SaaS selloff, why not all software companies face the same AI-driven risk...

23
Ben Thompson: Anthropic, the Pentagon, and the Limits of Private Power

Ben Thompson: Anthropic, the Pentagon, and the Limits of Private Power

Mar 05, 2026

In this conversation, previously aired on TBPN, John Coogan and Jordi Hays speak with Ben Thompson, founder of Stratechery, about his essay "Anthropic and Alignment" and the broader collision between ...

24
Deploying AI in Healthcare

Deploying AI in Healthcare

Mar 04, 2026

a16z general partner Julie Yoo talks with Nikhil Buduma, CEO and cofounder of Ambience Healthcare, to discuss how AI is transforming clinical workflows. They cover the early days of deep learning, why...

25
Ben Horowitz On What Makes a Great Founder

Ben Horowitz On What Makes a Great Founder

Mar 03, 2026

On the show Long Strange Trip, Sequoia Capital partner Brian Halligan speaks with a16z’s Ben Horowitz about what separates great founder CEOs from everyone else. Ben explains why first-time founders l...

26
Chris Dixon: From Quant Trading to Building a16z Crypto

Chris Dixon: From Quant Trading to Building a16z Crypto

Mar 02, 2026

In this feed drop from the Internet History Podcast, host Brian McCullough speaks with Chris Dixon, general partner at a16z, about his path from 1980s hobbyist programmer to one of the most prominent ...

27
a16z's New Media Playbook

a16z's New Media Playbook

Feb 27, 2026

Erik Torenberg, Ben Horowitz, and Marc Andreessen discuss how the media landscape has fundamentally changed and what a16z is doing about it. They cover why offense beats defense, why individuals now m...

28
When Giants Don’t Go Public: Inside the $5 Trillion Private Tech Market

When Giants Don’t Go Public: Inside the $5 Trillion Private Tech Market

Feb 26, 2026

Bloomberg's Odd Lots hosts Joe Weisenthal and Tracy Alloway speak with David George, general partner at a16z and head of the firm's growth fund, about why $5 trillion in tech market cap now sits in th...

29
Ben Horowitz: RSI, Crypto as AI Money, & Classified Physics

Ben Horowitz: RSI, Crypto as AI Money, & Classified Physics

Feb 23, 2026

Moonshots host Peter Diamandis speaks with Ben Horowitz, cofounder and general partner at a16z, alongside regular cohosts Salim Ismail, Dave Blundin, and Dr. Alexander Wissner-Gross, about whether AI ...

30
Patrick Collison on Stripe’s Early Choices, Smalltalk, and What Comes After Coding

Patrick Collison on Stripe’s Early Choices, Smalltalk, and What Comes After Coding

Feb 20, 2026

Michael Truell, CEO of Cursor, sits down with Patrick Collison, CEO of Stripe and an investor in Anysphere, to talk about Collison's history with Smalltalk and Lisp, the MongoDB and Ruby decisions Str...

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