The a16z Show

The a16z Show

Andreessen Horowitz

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Episode (200)

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31
Ben Horowitz on AI Infrastructure, Economics and The New Laws of Software

Ben Horowitz on AI Infrastructure, Economics and The New Laws of Software

Apr 14, 2026

Recorded live at the a16z Fintech Connect conference in Deer Valley, Alex Rampell speaks with Ben Horowitz, cofounder and general partner at a16z, about how AI has rewritten the fundamental rules of s...

32
Building Agents at Home: Parenting, Work, and Benevolent Neglect

Building Agents at Home: Parenting, Work, and Benevolent Neglect

Apr 13, 2026

Katherine Boyle and Sarah Wang speak with Jesse Genet, a startup founder and family builder, about building 11 AI agents while homeschooling four young children. Jesse runs agents across roles ranging...

33
What Running Windows at Microsoft Taught Steven Sinofsky About Apple

What Running Windows at Microsoft Taught Steven Sinofsky About Apple

Apr 10, 2026

Theo Jaffee speaks with Steven Sinofsky, board partner at a16z and former president of the Windows division at Microsoft, about Apple's 50th anniversary, the cultural differences that separated Apple ...

34
Who Controls AI Acceleration? Vitalik Buterin and Guillaume Verdon Debate

Who Controls AI Acceleration? Vitalik Buterin and Guillaume Verdon Debate

Apr 09, 2026

Eddy Lazzarin speaks with Vitalik Buterin, founder of Ethereum, and Guillaume Verdon, founder and CEO of Extropic, about whether AI progress can or should be steered, the risks of concentrated power, ...

35
The Agent Era: Building Software Beyond Chat with Box CEO Aaron Levie

The Agent Era: Building Software Beyond Chat with Box CEO Aaron Levie

Apr 08, 2026

Erik Torenberg, Steve Sinofsky, and Martin Casado speak to Aaron Levie, CEO at Box, about what happens to enterprise software when agents become the primary users. They discuss why coding agents succe...

36
Balaji on Why AI Raises the Cost of Verification

Balaji on Why AI Raises the Cost of Verification

Apr 07, 2026

a16z general partner Erik Torenberg speaks with Balaji Srinivasan, angel investor and entrepreneur, about why AI simultaneously reduces the cost of creation and increases the cost of verification, and...

37
Peter Yang on Small Teams, Coding Agents, and Why Human Ambition Has No Ceiling

Peter Yang on Small Teams, Coding Agents, and Why Human Ambition Has No Ceiling

Apr 06, 2026

Anish Acharya speaks with Peter Yang, creator and product lead at Roblox, about how personal AI agents are replacing the apps we open every day, why coding agents feel like slot machines, and what hap...

38
Marc Andreessen on AI Winters and Agent Breakthroughs

Marc Andreessen on AI Winters and Agent Breakthroughs

Apr 03, 2026

This episode originally aired on the Latent Space Podcast. swyx and Alessio Fanelli speak with Marc Andreessen about the arc of AI from its origins in 1943 to today's breakthroughs in reasoning, codin...

39
Alex Blania on Proof of Human and Building World's Identity Network

Alex Blania on Proof of Human and Building World's Identity Network

Apr 02, 2026

a16z's Ben Horowitz and Erik Torenberg speak with Alex Blania, cofounder and CEO of Tools for Humanity, World, and cofounder of Merge Labs. World is building the largest real human network, a proof-of...

40
What Happens When a Public Company Goes All In on AI

What Happens When a Public Company Goes All In on AI

Apr 01, 2026

David Haber speaks with Owen Jennings, executive officer and business lead at Block, about how the company rebuilt itself around AI agents, small squads, and internal tools like Goose and Builder Bot ...

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