Episode (200)
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Marc Andreessen on Builder Culture in the Age of AI
May 11, 2026Erik Torenberg speaks with Marc Andreessen about the state of AI, media, and the broader cultural and economic shifts shaping the internet. They discuss how narratives around AI, from fear to hype, ar...
Ben Horowitz on the Next Technology Era
May 08, 2026David Ulevitch speaks with Ben Horowitz about what it means to lead the technology industry at scale, and the responsibilities that come with it. Following the firm’s largest-ever fundraise, they disc...
Crypto Fund 5: We Raised $2.2B. Here’s Why.
May 07, 2026Robert Hackett speaks with the general partners at a16z crypto about the launch of their fifth crypto fund and the current state of the industry. They reflect on how crypto has evolved from an ideolog...
The New Space Race: NASA, Artemis, and the Race to the Moon
May 06, 2026Morgan Brennan speaks with NASA Administrator Jared Isaacman about the next phase of American space exploration and the urgency behind returning to the moon. They discuss the Artemis program, the chal...
Building Blackstone, Backing Costco, with Tony James
May 05, 2026David Haber speaks with Tony James about building enduring firms across multiple eras of finance. From joining DLJ when it was a subscale firm to helping grow Blackstone into one of the largest asset ...
Sarah Rogers: Free Speech, AI Diplomacy, and What America Owes Its Allies
May 04, 2026Katherine Boyle speaks with Sarah Rogers, Under Secretary for Public Diplomacy, about the intersection of AI, free speech, and global information systems. They discuss how major technological shifts, ...
Balaji and Taylor Lorenz on AI and Media
May 01, 2026Theo Jaffee speaks with Balaji Srinivasan and Taylor Lorenz about how AI is reshaping media, trust, and online communication. Building on prior public disagreements between the two, the conversation r...
Workday’s Last Workday? AI and the Future of Enterprise Software
Apr 30, 2026Elena Burger speaks with Joe Schmidt, partner on the enterprise team at a16z, about the future of enterprise software in the age of AI. Using Workday as a case study, they discuss why many of today’s ...
The Shift in Global Drug Development
Apr 29, 2026Theo Jaffee and Gabriel Dickinson speak with Cremieux about China’s rapid rise to the top of global clinical trial output. They discuss the regulatory reforms that accelerated China’s progress, the su...
John and Patrick Collison on Stripe's Growth, Agent Commerce, and the Future of Software
Apr 28, 2026This interview with Stripe cofounders John and Patrick Collison originally aired on TBPN. They discuss Stripe's 34% growth and new employee tender offer, how agent commerce and stablecoins may require...