The Human Upgrade: Biohacking for Longevity & Performance

The Human Upgrade: Biohacking for Longevity & Performance

Dave Asprey

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Episode (200)

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61
Biohackers in the Epstein Files, Generic GLP-1s, Continuous Ketone Monitors, and more...

Biohackers in the Epstein Files, Generic GLP-1s, Continuous Ketone Monitors, and more...

Feb 06, 2026

This episode covers:  • Longevity Influence In The Epstein Files  A new DOJ document release tied to the Epstein investigation pulled physician and longevity influencer Peter Attia into the spotlight...

62
Why 18-Year-Olds Wake Up Fresh (And You Don't)

Why 18-Year-Olds Wake Up Fresh (And You Don't)

Feb 05, 2026

18-year-olds wake up fresh because their repair system still works. This episode shows you how stem cell decline quietly drives fatigue, inflammation, and faster aging, and how fasting can reactivate ...

63
STOP Intermittent Fasting If You Want to Stay Young

STOP Intermittent Fasting If You Want to Stay Young

Feb 03, 2026

STOP intermittent fasting if you think it automatically keeps you young. In this episode, you’ll learn why short-term fasting results can mislead long-term aging outcomes, and how duration, frequency,...

64
Aging Starts In Your Legs (Here’s The Fix)

Aging Starts In Your Legs (Here’s The Fix)

Feb 01, 2026

Most people think aging starts with wrinkles, gray hair, or memory loss. It doesn’t. Aging starts when your legs begin to weaken, long before you notice it. In this video, you’ll learn why your leg m...

65
The Nobel Prize Molecule That Nearly Doubles Lifespan

The Nobel Prize Molecule That Nearly Doubles Lifespan

Jan 30, 2026

In the late 1990s, a strange carbon molecule quietly delivered the single longest lifespan extension ever recorded in mammals. The rats lived about 90% longer, and almost no one was paying attention. ...

66
Meet the Governor Who Wants Humans to Become Cyborgs

Meet the Governor Who Wants Humans to Become Cyborgs

Jan 29, 2026

Aging is not something Zoltan Istvan plans to accept quietly. He wants to treat death like a technical bug, rewrite the rules of biology, and turn California into the global test bed for radical human...

67
Your Butt is a Longevity Organ (Here’s how to train it!) | Gabrielle Lyon

Your Butt is a Longevity Organ (Here’s how to train it!) | Gabrielle Lyon

Jan 27, 2026

Your butt is not about aesthetics. It is a longevity organ that directly impacts metabolism, brain optimization, resilience, and how long you stay strong as you age. In this episode, you’ll learn why ...

68
The Natural Ozempic In Your Gut (Eat THIS To Switch It On)

The Natural Ozempic In Your Gut (Eat THIS To Switch It On)

Jan 25, 2026

Your gut already has its own version of Ozempic, and it’s been doing this job long before injections existed. In this video, I explain how appetite is actually regulated, why synthetic shortcuts ofte...

69
Biohacking News Weekly Update

Biohacking News Weekly Update

Jan 23, 2026

This episode covers:  • Real Food Reset in U.S. Dietary Policy  The new Dietary Guidelines for Americans 2025–2030 put real food back at the center of U.S. nutrition policy and take a direct swing at...

70
This Brain Trick Feels Like Cheating (Do THIS)

This Brain Trick Feels Like Cheating (Do THIS)

Jan 22, 2026

Most brain decline, mood instability, and impulsive behavior start with a breakdown in how the brain’s immune cells produce and use energy. This episode shows how mitochondrial health inside microglia...

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