The GLP-1 Business Model Problem | Ep. 1. with Prof. Alex Miras

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The GLP-1 Business Model Problem | Ep. 1. with Prof. Alex Miras

Ash Sharma

13 February 2026

In this debut episode, Ashwin Sharma sits down with Professor Alex Miras, one of the world's leading obesity medicine specialists, to discuss the economics of GLP-1 medications. They cover: 1. Why the drug does the heavy lifting (not willpower) 2. Why price is the only barrier that matters 3. Why the muscle loss panic is probably a measurement problem 4. The oral GLP-1 revolution and what it means for patients 5. Food noise - the huge mistake clinicians are making Prof. Miras brings 15+ years of clinical and research experience from Imperial College London and King's College Hospital. Subscribe to the GLP-1 Digest newsletter for weekly analysis: www.glp1digest.com Watch the full video version on YouTube: https://youtu.be/PF7fF8vclic