No Priors: Artificial Intelligence | Technology | Startups

No Priors: Artificial Intelligence | Technology | Startups

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Episode (156)

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21
Humans&: Bridging IQ and EQ in Machine Learning with Eric Zelikman

Humans&: Bridging IQ and EQ in Machine Learning with Eric Zelikman

Oct 09, 2025

The AI industry is obsessed with making models smarter. But what if they’re building the wrong kind of intelligence? In launching his new venture, humans&, Eric Zelikman sees an opportunity to shift t...

22
The Impact of AI, from Business Models to Cybersecurity, with Palo Alto Networks CEO Nikesh Arora

The Impact of AI, from Business Models to Cybersecurity, with Palo Alto Networks CEO Nikesh Arora

Oct 04, 2025

Between the future of search, the biggest threats in cybersecurity, and the jobs and platforms of tomorrow, Nikesh Arora sees one common thread connecting and transforming them all—AI. Sarah Guo and E...

23
Reinventing K-12 Education Using AI with Alpha School Principal Joe Liemandt

Reinventing K-12 Education Using AI with Alpha School Principal Joe Liemandt

Sep 25, 2025

What if kids could master their academics in just two hours a day and spend the rest of their time developing real-world skills they’re passionate about? Joe Liemandt, founder of the software company ...

24
AI Agents Talking to AI Agents: Reinventing Commerce with Decagon CEO Jesse Zhang

AI Agents Talking to AI Agents: Reinventing Commerce with Decagon CEO Jesse Zhang

Sep 18, 2025

The traditional call center may soon be a thing of the past. Jessie Zhang is building AI agents designed to replace monotonous human labor and transform how consumers interact with brands. Elad Gil si...

25
Jared Kushner: BrainCo, Affinity Partners, and the Geopolitics of AI

Jared Kushner: BrainCo, Affinity Partners, and the Geopolitics of AI

Sep 15, 2025

From negotiating with world leaders to partnering with top entrepreneurs, businessman and investor Jared Kushner has traveled the unique path of bringing private sector knowledge to government work an...

26
A New Operating System for Physicians with OpenEvidence Founder Daniel Nadler

A New Operating System for Physicians with OpenEvidence Founder Daniel Nadler

Sep 05, 2025

How does a new technology get adopted by 40% of American doctors in just 18 months? In an era where the golden age of biotechnology has also created a dark age of physician burnout, OpenEvidence found...

27
Reshaping America’s Economy for the Superintelligence Century with Jacob Helberg

Reshaping America’s Economy for the Superintelligence Century with Jacob Helberg

Aug 28, 2025

AI doomers say that the technology will be the ultimate job-killer. But Jacob Helberg wants people to see AI as a tech that will boost, not replace, human workers and give them superpowers. Under Secr...

28
How Agentic AI is Transforming The Startup Landscape with Andrew Ng

How Agentic AI is Transforming The Startup Landscape with Andrew Ng

Aug 21, 2025

Andrew Ng has always been at the bleeding edge of fast-evolving AI technologies, founding companies and projects like Google Brain, AI Fund, and DeepLearning.AI. So he knows better than anyone that fo...

29
Chips, Neoclouds, and the Quest for AI Dominance with SemiAnalysis Founder and CEO Dylan Patel

Chips, Neoclouds, and the Quest for AI Dominance with SemiAnalysis Founder and CEO Dylan Patel

Aug 14, 2025

What would it take to challenge Nvidia? SemiAnalysis Founder and CEO Dylan Patel joins Sarah Guo to answer this and other topical questions around the current state of AI infrastructure. Together, the...

30
The Shifting Value of Content in the AI Age with Cloudflare CEO Matthew Prince

The Shifting Value of Content in the AI Age with Cloudflare CEO Matthew Prince

Aug 07, 2025

Cloudflare has spent nearly fifteen years making the Internet faster, more reliable, and more secure. So now that AI systems are changing the way we interact with the Internet, Cloudflare wants to hel...

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