Invest Like the Best with Patrick O'Shaughnessy

Invest Like the Best with Patrick O'Shaughnessy

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Episode (200)

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11
Patrick O’Shaughnessy - Creating on Principle

Patrick O’Shaughnessy - Creating on Principle

Jan 20, 2026

This week is a special episode. Only David Senra could get me to be on the other side of the mic. Because I don’t plan on being interviewed often, I wanted to share this conversation, which I so enjoy...

12
Tom Digan & Greg Stewart - Building the World’s Best Fitness App

Tom Digan & Greg Stewart - Building the World’s Best Fitness App

Jan 13, 2026

My guests today are Tom Digan and Greg Stewart. Tom is the co-founder of Ladder, and Greg is its CEO. Ladder was my first angel investment. What followed over the next seven years is one of the most ...

13
Reed Hastings - Building Netflix

Reed Hastings - Building Netflix

Jan 06, 2026

My guest today is Reed Hastings, the co-founder and former longtime CEO of Netflix. Netflix is an example of two ideas that everyone talks about, but are extremely hard to do in practice. The first i...

14
Nick Kokonas - Know What You Are Selling

Nick Kokonas - Know What You Are Selling

Dec 30, 2025

Today, I am replaying my conversation with Nick Kokonas, one of my favorites from the show. Nick is the co-founder of 3 of the best restaurants and bars in America - Alinea, Next, and The Aviary as...

15
Ric Elias - The Art of Living Well

Ric Elias - The Art of Living Well

Dec 23, 2025

Ric Elias - The Art of Living Well - [Invest Like The Best, CLASSICS] Welcome to this classic episode. Classics are my favorite episodes from the past 10 years, published once a month. These are N of...

16
Henry Ellenbogen - Man Versus Machine

Henry Ellenbogen - Man Versus Machine

Dec 16, 2025

My guest today is Henry Ellenbogen, founder and Managing Partner of Durable Capital Partners. Henry built his reputation at T. Rowe Price, where he led the New Horizons Fund and turned it into one of ...

17
Gavin Baker - Nvidia v. Google, Scaling Laws, and the Economics of AI

Gavin Baker - Nvidia v. Google, Scaling Laws, and the Economics of AI

Dec 09, 2025

My guest this week is Gavin Baker. Gavin is the managing partner and CIO of Atreides Management, and he has been on the show many times before.  I will never forget when I first met Gavin in 2017. I ...

18
David George - Building a16z Growth, Investing Across the AI Stack, and Why Markets Misprice Growth

David George - Building a16z Growth, Investing Across the AI Stack, and Why Markets Misprice Growth

Dec 02, 2025

My guest today is David George. David is a General Partner at Andreessen Horowitz, where he leads the firm’s growth investing business. His team has backed many of the defining companies of this era –...

19
Palmer Luckey - Inventing the Future of Defense

Palmer Luckey - Inventing the Future of Defense

Nov 28, 2025

Welcome to this classic episode. Classics are my favorite episodes from the past 10 years, published once a month. These are N of 1 conversations with N of 1 people. Palmer Luckey is a relentless buil...

20
Martín Escobari - Inside General Atlantic

Martín Escobari - Inside General Atlantic

Nov 25, 2025

My guest today is Martín Escobari. Martín is Co-President and Head of Global Growth Equity at General Atlantic. We talk about General Atlantic’s unique founding story and how its long-term structure,...

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